Allergen-specific IgE, synthesized in response to allergens, becomes fixed to receptors on cellular membranes, especially those of basophils. If these receptor-bound IgE molecules are aggregated on re-exposure to specific allergen, both mast cells and basophils produce mediators that result in the allergic response. IgE-antigen interaction at the cell surface causes degranulation of cells and release of substances including: histamine, SRS-A, platelet activator, a kallikrein, and an eosinophil chemotactic factor. Basophils are the principal cells that bind IgE antibody while their number of receptor sites is proportional to serum IgE levels. Eosinophils are drawn to the site by the basophil chemotaxis mechanism, but are not the main cell which binds the IgE antibody.

Immunology

The mediator cells that bind MOST to IgE antibodies are:

A. Basophils

B. Eosinophils

C. Polymorphonuclear neutrophils

D. Macrophages

The electrolyte panel consists of potassium, sodium, chloride, carbon dioxide. These analytes are also typically ordered within other panels as well, including the basic metabolic and complete metabolic panels.

An electrolyte panel (lytes, chem-4) consists of:

A. Potassium, Sodium, Chloride, Carbon dioxide

B. Potassium, Sodium, Chloride, Glucose

C. Potassium, Sodium, Chloride, Creatinine

D. Potassium, Sodium, Chloride, BUN

Which of the following statements applies to the venipuncture procedure?

A. Standard Precautions must be observed

B. the procedure includes preparation of the patient

C. selecting and preparing the puncture site is part of the procedure

D. all of the above

A clinical laboratory scientist or medical laboratory scientist (or medical technologist in older terminology) may serve as all of the following except:

A. laboratory manager.

B. pathologist.

C. section supervisor.

D. educator.

What amount of absorbent material must be included between the primary receptacle and secondary packaging for either a category A or category B liquid specimen?

A. At least enough to surround the primary receptacle

B. Enough to completely absorb the specimen if the container leaked or broke

C. Enough to fill the space between the primary receptacle and the secondary container

D. There is no requirement for absorbent material